hERG Screening
Evaluate compound effects on hERG potassium channel currents through routine screening and testing under physiological-temperature conditions.
hERG ScreeningPhysiological-Temperature hERG ScreeningFrom ion channels and cardiomyocytes to cardiac organoids and isolated hearts, electrophysiology and Functional Imaging provide experimental support for drug discovery and cardiac function research.
Select an experimental platform according to the research model and evaluation objectives.
Evaluate compound effects on hERG potassium channel currents through routine screening and testing under physiological-temperature conditions.
hERG ScreeningPhysiological-Temperature hERG ScreeningPrimary and iPSC-derived cardiomyocytes and cardiac organoids can be evaluated using action potentials, calcium imaging, voltage imaging, contraction and coupling assays. Field potential, impedance or contraction mechanics approaches are selected according to culture conditions.
View servicePrimary Cardiomyocyte Functional AssaysiPSC-Derived Cardiomyocyte Functional AssaysCardiac Organoid and Cardiac Tissue-Like Model AssaysUse the Langendorff perfusion platform to observe electrocardiographic activity, rhythm and ventricular pressure and study drug effects on cardiac function.
Langendorff Isolated Heart PerfusionEvaluate in vitro cell models for pulsed field ablation (PFA) research, with related services covering experimental design and functional assays.
In Vitro Cell Models for Pulsed Field AblationPulsed Field Ablation In Vitro TestingFrom ion channel currents to cardiac action potentials, examine electrophysiological changes and drug responses.
View serviceCombine calcium transients and contraction-related parameters to study cardiac functional phenotypes.
View serviceDiscuss suitable experimental models in relation to the research objectives, sample conditions and evaluation endpoints.
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