With electrophysiology and Functional Imaging at the core, complemented by histopathology and multi-omics analysis, select platforms for drug discovery and basic research spanning cellular function, tissue phenotypes and molecular changes.
From Functional Assays to Tissue and Molecular Analysis
Cellular Functional Imaging
Perform voltage and calcium imaging in neurons, cardiomyocytes and other compatible models to analyze dynamic functional signals and changes under different treatment conditions.
Record membrane potential and ionic currents in cells, neurons and acute slices to analyze action potentials, synaptic activity and pharmacological responses.
From tissue processing, sectioning and routine staining to applicable molecular labeling and quantitative analysis, examine tissue structure and cellular phenotypes to provide histopathology support for research projects.
Select assays and bioinformatics analysis approaches for research in genomics, transcriptomics, epigenomics, single-cell analysis, proteomics and metabolomics.
Select Assay Platforms According to Research Endpoints
Dynamic Function and Pharmacological Responses
Use patch clamp, voltage imaging and calcium imaging to examine changes in cellular electrical activity and calcium signals, supporting functional characterization and candidate compound research.
Use tissue sections, staining and corresponding image analysis to investigate morphological changes and marker distribution. Sample processing conditions need to match the intended endpoints.
Select omics assays according to the research objective and combine differential analysis, pathway enrichment and applicable integrative analysis to generate mechanistic insights for further validation.
Specify the sample type, research question and required endpoints, and select a single assay platform or complementary experimental methods.
Confirm Experimental Compatibility
Check sample storage, culture or fixation conditions and establish the control design and analysis parameters. Different platforms may require separately prepared samples.
Interpret Results in Relation to the Research Question
Relate functional, tissue-level or molecular results to the original research objectives, and analyze changes and their scope of interpretation according to the project plan.